Ammonium → Tert-butyl 3-[(2,3-difluorophenyl)-(2-ethoxy-2-oxoethoxy)methyl]piperidine-1-carboxylate
Reaction equation
[Br:26][CH2:27][C:28](=[O:29])[O:30][CH2:31][CH3:32].[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[Cl-:33].[F:3][c:4]1[c:5]([CH:11]([CH:12]2[CH2:13][N:14]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:15][CH2:16][CH2:17]2)[OH:25])[cH:6][cH:7][cH:8][c:9]1[F:10].[H-:2].[NH4+:34].[Na+:1]>>[F:3][c:4]1[c:5]([CH:11]([CH:12]2[CH2:13][N:14]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:15][CH2:16][CH2:17]2)[O:25][CH2:27][C:28](=[O:29])[O:30][CH2:31][CH3:32])[cH:6][cH:7][cH:8][c:9]1[F:10]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-e357d8b4eb054a0b90c88f2fa286733f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…