Hydrochloric Acid → 4-(4-Chloro-2-fluorophenoxy)-6-methoxy-7-((4-pyridyl)methoxy)quinazoline
Reaction equation
[C:23](=[O:24])([O-:25])[O-:26].[Cl:1][c:2]1[cH:3][c:4]([F:22])[c:5]([O:6][c:7]2[n:8][cH:9][n:10][c:11]3[cH:12][c:13]([OH:19])[c:14]([O:17][CH3:18])[cH:15][c:16]23)[cH:20][cH:21]1.[Cl:30][CH2:31][c:32]1[cH:33][cH:34][n:35][cH:36][cH:37]1.[ClH:29].[K+:27].[K+:28].[O:38]=[CH:39][N:40]([CH3:41])[CH3:42]>>[Cl:1][c:2]1[cH:3][c:4]([F:22])[c:5]([O:6][c:7]2[n:8][cH:9][n:10][c:11]3[cH:12][c:13]([O:19][CH2:31][c:32]4[cH:33][cH:34][n:35][cH:36][cH:37]4)[c:14]([O:17][CH3:18])[cH:15][c:16]23)[cH:20][cH:21]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-1fa73eec69bd4eb1bf733927ed77b954
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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