2,4-Dihydroxy-3-allylbenzophenone → (2,4-Dihydroxy-3-propylphenyl)(phenyl)methanone

HRID 1727283Notes

Reaction equation

HRID 1727283 reaction equation
[OH:1][C:2]1[C:15]([CH2:16][CH:17]=[CH2:18])=[C:14]([OH:19])[CH:13]=[CH:12][C:3]=1[C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)=[O:5]>C(OCC)(=O)C.[Pd]>[OH:1][C:2]1[C:15]([CH2:16][CH2:17][CH3:18])=[C:14]([OH:19])[CH:13]=[CH:12][C:3]=1[C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)=[O:5]

Participants

4

Reactant 1

HCID 219109812,4-Dihydroxy-3-allylbenzophenone

Product 1

HCID 13019373(2,4-Dihydroxy-3-propylphenyl)(phenyl)methanone

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

A solution of 2,4-dihydroxy-3-(2-propenyl)benzophenone (3 g) was reduced under ˜1 atm H2 in ethyl acetate (100 mL) over 10% Pd/C catalyst (0.3 grams) for 3 hours. The product was purified by crystallization from methanol/water. The product is obtained as small yellow plates.

Workup

  1. customThe product was purified by crystallization from methanol/water
  2. customThe product is obtained as small yellow plates

Sources & evidence

ORD record
ord-de268f8f414d4757a863a9b72dc3d063
Source dataset
uspto-grants-2009_02
Patent number
US07495020B2

Reaction notes

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