Hydrochloric Acid → 2-Methyl-2-{3-[1-(4-trifluoromethyl-benzylcarbamoyl)-piperidin-3-yl]-phenoxy}-propionic acid benzyl ester
Reaction equation
[C:13](=[O:14])([n:15]1[cH:16][cH:17][n:18][cH:19]1)[n:20]1[cH:21][cH:22][n:23][cH:24]1.[CH2:25]([c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1)[O:32][C:33]([C:34]([CH3:35])([O:36][c:37]1[cH:38][c:39]([CH:43]2[CH2:44][NH:45][CH2:46][CH2:47][CH2:48]2)[cH:40][cH:41][cH:42]1)[CH3:49])=[O:50].[CH3:52][c:53]1[cH:54][cH:55][cH:56][cH:57][cH:58]1.[ClH:51].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([CH2:7][NH2:8])[cH:9][cH:10]1)([F:11])[F:12].[OH2:59]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([CH2:7][NH:8][C:13](=[O:14])[N:45]2[CH2:44][CH:43]([c:39]3[cH:38][c:37]([O:36][C:34]([C:33]([O:32][CH2:25][c:26]4[cH:27][cH:28][cH:29][cH:30][cH:31]4)=[O:50])([CH3:35])[CH3:49])[cH:42][cH:41][cH:40]3)[CH2:48][CH2:47][CH2:46]2)[cH:9][cH:10]1)([F:11])[F:12]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-98e728115ef241c78d4099295a88d783
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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