Tetrahydrofuran → 4-(2-Fluoro-4-methylphenylamino)-1,2,5-trimethyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid cyclopropylmethoxy-amide
Reaction equation
[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[CH2:7]([O:9][C:10](=[O:8])[c:12]1[c:13]([CH3:30])[n:14]([CH3:29])[c:15](=[O:28])[c:16]([CH3:27])[c:17]1[NH:18][c:19]1[c:20]([F:26])[cH:21][c:22]([CH3:25])[cH:23][cH:24]1)[CH3:11].[CH3:31][Si:32]([N-:33][Si:34]([CH3:35])([CH3:36])[CH3:37])([CH3:38])[CH3:39].[CH:1]1([CH2:4][O:5][NH2:6])[CH2:2][CH2:3]1.[Li+:40]>>[CH:1]1([CH2:4][O:5][NH:6][C:10](=[O:9])[c:12]2[c:13]([CH3:30])[n:14]([CH3:29])[c:15](=[O:28])[c:16]([CH3:27])[c:17]2[NH:18][c:19]2[c:20]([F:26])[cH:21][c:22]([CH3:25])[cH:23][cH:24]2)[CH2:2][CH2:3]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-2945b3a7c4b2424fb5f1e89d9719fcf2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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