(+-)-2-Undecanol → 2-Methanesulfonyloxyundecane

HRID 1728286ノート

反応式

HRID 1728286 の反応式
[CH3:1][S:2]([O:5][CH:6]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])[CH3:7])(=[O:4])=[O:3].[CH3:16]C(O)CCCCCCCCC.CS(Cl)(=O)=O.C(N(C(C)C)CC)(C)C>C(Cl)Cl>[CH3:1][S:2]([O:5][CH:6]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[CH3:7])(=[O:4])=[O:3]

参加物

6

反応物 4

HCID 15448(+-)-2-UndecanolHCID 31297Methanesulfonyl chlorideHCID 81531DiisopropylethylamineHCID 14916009Decan-2-yl methanesulfonate

生成物 1

HCID 153433162-Methanesulfonyloxyundecane収率 95%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

2-Methanesulfonyloxyundecane was prepared as described for 2-methanesulfonyloxydecane from 2-undecanol (30.0 ml, 144 mmol), methanesulfonylchloride (15.5 ml, 200 mmol) and diisopropylethylamine (30.8 ml, 177 mmol) in dry CH2Cl2 (240 ml). After stirring for 3.5 hrs, the reaction was processed as previously stated but at 4 times the volumes to provide 2-methanesulfonyloxyundecane (31.35 g, 95%).

後処理

  1. custom2-Methanesulfonyloxyundecane was prepared

出典と根拠

ORDレコード
ord-2389d1d0164c45bb9b0646f32866c50e
出典データセット
uspto-grants-1994_07
特許番号
US05326553

反応ノート

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