Dichloromethane → HCID 19018249, compound

HRID 1728451Notes

Reaction equation

HRID 1728451 reaction equation
Br[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9]CC(O)=O)=[CH:5][CH:4]=1.[C:14](Cl)(=O)[C:15]([Cl:17])=[O:16].[Cl:20]CCl>>[Cl:20][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:14][C:15]([Cl:17])=[O:16])=[CH:5][CH:4]=1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 65578Oxalyl chlorideHCID 19018242HCID 19018242, compound

Product 1

HCID 19018249HCID 19018249, compound

Procedure

A solution of 1.5 g (6.2 mmol) of 3-[4-(bromomethyl)phenyl]propionic acid (U.S. Pat. No. 4,032,533) and 1.2 g (9.3 mmol) of oxalyl chloride in 6 ml of dichloromethane was stirred at room temperature for 2.5 hours and evaporated to give 1.6 g of product as an oil.

Workup

  1. customevaporated

Sources & evidence

ORD record
ord-2f5afa9dd90d48d7938ed920add6dfcd
Source dataset
uspto-grants-1994_07
Patent number
US05326905

Reaction notes

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