Methyl iodide → 2-[[Acetyl[3-(tetradecyloxy)benzoyl]amino]methyl]-1-methylpyridinium iodide

HRID 1728814노트

반응식

HRID 1728814 반응식
[C:1]([N:4]([CH2:28][C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][N:30]=1)[C:5](=[O:27])[C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])[CH:7]=1)(=[O:3])[CH3:2].[CH3:35][I:36]>>[I-:36].[C:1]([N:4]([CH2:28][C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][N+:30]=1[CH3:35])[C:5](=[O:27])[C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])[CH:7]=1)(=[O:3])[CH3:2]

참가 물질

3

반응물 2

HCID 6328Methyl iodideHCID 10367289N-Acetyl-N-(2-pyridinylmethyl)-3-(tetradecyloxy)benzamide

생성물 1

HCID 104162732-[[Acetyl[3-(tetradecyloxy)benzoyl]amino]methyl]-1-methylpyridinium iodide수율 98%

실험 절차

The title compound is prepared by the procedure of Example 28, using 1.08 g of product from Example 29 and 16.36 g of methyl iodide. The residue is recrystallized from methyl alcohol to give 1.38 g of the desired product as yellow crystals with hygroscopic properties.

후처리

  1. customThe title compound is prepared by the procedure of Example 28
  2. customThe residue is recrystallized from methyl alcohol

출처 및 근거

ORD 기록
ord-141d72d42250406a9e2bdfcc41767006
출처 데이터셋
uspto-grants-1994_07
특허 번호
US05328921

반응 노트

불러오는 중…