Methyl iodide → 2-[[Acetyl[3-(tetradecyloxy)benzoyl]amino]methyl]-1-methylpyridinium iodide

HRID 1728814Notes

Reaction equation

HRID 1728814 reaction equation
[C:1]([N:4]([CH2:28][C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][N:30]=1)[C:5](=[O:27])[C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])[CH:7]=1)(=[O:3])[CH3:2].[CH3:35][I:36]>>[I-:36].[C:1]([N:4]([CH2:28][C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][N+:30]=1[CH3:35])[C:5](=[O:27])[C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])[CH:7]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 10367289N-Acetyl-N-(2-pyridinylmethyl)-3-(tetradecyloxy)benzamide

Product 1

HCID 104162732-[[Acetyl[3-(tetradecyloxy)benzoyl]amino]methyl]-1-methylpyridinium iodideYield 98%

Procedure

The title compound is prepared by the procedure of Example 28, using 1.08 g of product from Example 29 and 16.36 g of methyl iodide. The residue is recrystallized from methyl alcohol to give 1.38 g of the desired product as yellow crystals with hygroscopic properties.

Workup

  1. customThe title compound is prepared by the procedure of Example 28
  2. customThe residue is recrystallized from methyl alcohol

Sources & evidence

ORD record
ord-141d72d42250406a9e2bdfcc41767006
Source dataset
uspto-grants-1994_07
Patent number
US05328921

Reaction notes

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