Hydrochloric Acid → HCID 10997132, compound

HRID 1728980Notes

Reaction equation

HRID 1728980 reaction equation
C[O:2][C:3]([C@@H:5]1[C@H:9]([CH3:10])[CH2:8][C:7](=[O:11])[CH2:6]1)=[O:4].Cl>>[C:3]([C@@H:5]1[C@H:9]([CH3:10])[CH2:8][C:7](=[O:11])[CH2:6]1)([OH:4])=[O:2]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 13451547HCID 13451547, compound

Product 1

HCID 10997132HCID 10997132, compoundYield 79.9%

Procedure

1.18 g of (3S, 4R)-3-methoxycarbonyl-4-methylcyclopentanone was added to 20 ml of 3N-hydrochloric acid, and the mixture was refluxed for 2 hours. The resultant mixture was cooled down to room temperature, and concentrated to dryness. The residue was purified by distillation under a reduced pressure, and thus 0.858 g of the titled compound was obtained.

Workup

  1. temperaturethe mixture was refluxed for 2 hours
  2. concentrationconcentrated to dryness
  3. distillationThe residue was purified by distillation under a reduced pressure

Sources & evidence

ORD record
ord-985eaa37d2ae4d1da45eeea1e0b31458
Source dataset
uspto-grants-1994_07
Patent number
US05329042

Reaction notes

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