Saccharin → HCID 131718560, compound

HRID 1729037Notes

Reaction equation

HRID 1729037 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([CH:11]2[CH2:20][C:19]3[C:14](=[CH:15][C:16]([CH3:21])=[CH:17][CH:18]=3)[CH2:13][N:12]2[CH3:22])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[S:23]1([C:34]2[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=2)[C:27](=[O:28])[NH:26]1)(=[O:25])=[O:24]>CO>[S:23]1([C:34]2[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=2)[C:27](=[O:28])[NH:26]1)(=[O:24])=[O:25].[C:1]([C:5]1[CH:6]=[CH:7][C:8]([CH:11]2[CH2:20][C:19]3[C:14](=[CH:15][C:16]([CH3:21])=[CH:17][CH:18]=3)[CH2:13][N:12]2[CH3:22])=[CH:9][CH:10]=1)([CH3:4])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 5143SaccharinHCID 19013343HCID 19013343, compound

Product 1

HCID 131718560HCID 131718560, compoundYield 101.6%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In 10 ml of methanol, 0.20 g of 3-(4-tertbutylphenyl)-2,7-dimethyl-1,2,3,4-tetrahydroisoquinoline and 0.13g of saccharin were dissolved at room temperature under stirring, and the resulting mixture was left to stand for 3 hours. The solvent was evaporated under reduced pressure to obtain 0.33 g of 3-(4-tertbutylphenyl)-2,7-dimethyl-l,2,3,4-tetrahydroisoquinoline saccharin salt.

Workup

  1. waitthe resulting mixture was left
  2. customThe solvent was evaporated under reduced pressure

Sources & evidence

ORD record
ord-82eca635883a4d309d05c5973e8fac64
Source dataset
uspto-grants-1994_07
Patent number
US05330991

Reaction notes

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