4-Chlorophenol → HCID 19011810, compound

HRID 1729305Notes

Reaction equation

HRID 1729305 reaction equation
[Cl:1]C1C=CC(O)=CC=1.ClC1C=CC=CC=1O.[CH3:17][N:18]1[C:23]([N:24]2[CH2:29][CH2:28][N:27]([CH2:30][CH2:31][CH2:32][O:33][C:34]3[CH:39]=[CH:38][CH:37]=[CH:36][C:35]=3[Cl:40])[CH2:26][CH2:25]2)=[CH:22][C:21](=[O:41])[N:20]([CH3:42])[C:19]1=[O:43]>>[ClH:1].[CH3:17][N:18]1[C:23]([N:24]2[CH2:29][CH2:28][N:27]([CH2:30][CH2:31][CH2:32][O:33][C:34]3[CH:39]=[CH:38][CH:37]=[CH:36][C:35]=3[Cl:40])[CH2:26][CH2:25]2)=[CH:22][C:21](=[O:41])[N:20]([CH3:42])[C:19]1=[O:43]

Participants

4

Reactant 3

HCID 46844-ChlorophenolHCID 72452-ChlorophenolHCID 10091945HCID 10091945, compound

Product 1

HCID 19011810HCID 19011810, compound

Procedure

The same treatment as in Example 3 was effected except that 4-chlorophenol was replaced with 2-chlorophenol, thereby obtaining 8.2 g of the crystals of 1,3-dimethyl-6-[4-(3-[2-chlorophenoxy]propyl)piperazin-1-yl]-2,4(1H,3H)-pyrimidinedione.

Sources & evidence

ORD record
ord-9ddd8acdc3784c2b8ac4925c63378075
Source dataset
uspto-grants-1994_07
Patent number
US05332739

Reaction notes

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