Triethylamine → HCID 86748023, compound

HRID 1729460Notes

Reaction equation

HRID 1729460 reaction equation
[CH2:1]([C@@H:7]1[C@@H:12]([OH:13])[C:11]([CH3:16])([CH2:14][OH:15])[O:10][C:8]1=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[CH3:17][S:18](Cl)(=[O:20])=[O:19].C(N(CC)CC)C>C(Cl)Cl>[CH2:1]([C@@H:7]1[C@@H:12]([OH:13])[C:11]([CH3:16])([CH2:14][O:15][S:18]([CH3:17])(=[O:20])=[O:19])[O:10][C:8]1=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 86748020HCID 86748020, compound

Product 1

HCID 86748023HCID 86748023, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2-(R)-Hexyl-3-(R)-hydroxy-4-methyl-4-hydroxymethylbutyrolactone (prepared as described in example 7) is reacted with 1 eq. of methanesulfonylchloride and 3 eq. of triethylamine in dry methylene chloride at 0° C. to afford 2-(R)-hexyl-3-(R)-hydroxy-4-methyl-4-methanesulfonyloxymethylbutyrolactone

Sources & evidence

ORD record
ord-fb138d0e33ea4c828b9618e2f8ca304a
Source dataset
uspto-grants-1994_07
Patent number
US05332807

Reaction notes

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