Hydrochloric Acid → 3-(1,3,4,9b-Tetrahydro-5-methyl-2H-indeno[1,2-c]pyridin-2-yl)-N-methylpropionic acid amide

HRID 1729998Notes

Reaction equation

HRID 1729998 reaction equation
[CH3:1][C:2]1[C:3]2[C:8]([CH:9]3[C:14]=1[CH2:13][CH2:12][NH:11][CH2:10]3)=[CH:7][CH:6]=[CH:5][CH:4]=2.[CH3:15][NH:16][C:17](=[O:20])[CH:18]=[CH2:19].Cl>>[CH3:1][C:2]1[C:3]2[C:8]([CH:9]3[C:14]=1[CH2:13][CH2:12][N:11]([CH2:19][CH2:18][C:17]([NH:16][CH3:15])=[O:20])[CH2:10]3)=[CH:7][CH:6]=[CH:5][CH:4]=2

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 14471MethylacrylamideHCID 214987881,3,4,9b-tetrahydro-5-methyl-2H-indeno[1,2-c]pyridine

Product 1

HCID 681387243-(1,3,4,9b-Tetrahydro-5-methyl-2H-indeno[1,2-c]pyridin-2-yl)-N-methylpropionic acid amide

Procedure

1,3,4,9b-Tetrahydro-5-methyl-2H-indeno[1,2-C]pyridine and N-methyl acrylamide are reacted in accordance with the process described in Example 6. Reaction period 15 hours. M.P. of the hydrochloride of the title compound 200°-201° from ethanol.

Workup

  1. customReaction period 15 hours

Sources & evidence

ORD record
ord-cd71aac84622406ba4fe7daa84c1092c
Source dataset
uspto-grants-1976_11
Patent number
US03991066

Reaction notes

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