Hydrochloric Acid → 4-(4-Fluoro-phenyl)-2-isopropyl-7-pyrrolidin-1-yl-5,6,7,8-tetrahydro-quinazoline
Reaction equation
[Br:22][c:23]1[cH:24][cH:25][cH:26][c:27]([OH:28])[c:29]1[CH3:30].[C:36]([BH3-:37])#[N:38].[CH2:31]1[CH2:32][CH2:33][NH:34][CH2:35]1.[CH3:41][OH:42].[ClH:40].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]([CH:19]([CH3:20])[CH3:21])[n:11][c:12]3[c:17]2[CH2:16][CH2:15][C:14](=[O:18])[CH2:13]3)[cH:6][cH:7]1.[Na+:39]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]([CH:19]([CH3:20])[CH3:21])[n:11][c:12]3[c:17]2[CH2:16][CH2:15][CH:14]([N:34]2[CH2:33][CH2:32][CH2:31][CH2:35]2)[CH2:13]3)[cH:6][cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-6fb125c12f444e4d999970d3d73fc1e1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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