反应详情

Tritylchloride (61.2 g., 0.22 mole) is added to a mixture of 6-aminopenicillanic acid (43.3 g., 0.20 mole) and triethylamine (5.56 ml.)in chloroform (300 ml.) at about 5° C. The somewhat exothermic reaction is stirred and allowed to rise gradually to room temperature. It is stirred at room temperature for three days. Evaporation of the reactionmixture affords the title product which is used without purification.

1. customat about 5° C
2. customThe somewhat exothermic reaction
3. customto rise gradually to room temperature
4. stirringIt is stirred at room temperature for three days
5. customEvaporation of the reactionmixture