Hydrogen Bromide → gamma-Aminopropylhydroquinone.hydrobromide

HRID 1730437Notes

Reaction equation

HRID 1730437 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][C:5]1[CH:10]=[C:9]([O:11]C)[CH:8]=[CH:7][C:6]=1[O:13]C.[BrH:15]>>[BrH:15].[NH2:1][CH2:2][CH2:3][CH2:4][C:5]1[CH:10]=[C:9]([OH:11])[CH:8]=[CH:7][C:6]=1[OH:13]

Participants

3

Reactant 2

HCID 260Hydrogen BromideHCID 214979803-(2,5-Dimethoxyphenyl)propan-1-amine

Product 1

HCID 21390156gamma-Aminopropylhydroquinone.hydrobromideYield 69.3%

Procedure

100 g of γ-aminopropyl-2,5-dimethoxybenzene was heated at an oil bathtemperature of 180° C in 830 ml of 48% hydrobromic acid while blowing therein nitrogen gas. After the reaction, the reaction mixture wascooled, and the precipitated crystals were filtered out and dried to obtain88 g of the end product having a melting point of 130° ~ 131° C (yield 69.3%).

Workup

  1. customAfter the reaction
  2. filtrationthe precipitated crystals were filtered out
  3. customdried to obtain88 g of the end product

Sources & evidence

ORD record
ord-591c58fa673343aca1b1691cce4eb241
Source dataset
uspto-grants-1976_11
Patent number
US03992449

Reaction notes

Loading…