Hydrogen Peroxide → HCID 54303272, compound

HRID 1730752Notes

Reaction equation

HRID 1730752 reaction equation
[CH3:1][N:2]([CH3:22])[C:3](=[O:21])[CH2:4][S:5][CH:6]([C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[F:20])=[CH:10][CH:9]=1)[CH3:7].[OH:23]O.C1(C)C=CC=CC=1>C(O)(=O)C>[CH3:22][N:2]([CH3:1])[C:3](=[O:21])[CH2:4][S:5]([CH:6]([C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[F:20])=[CH:10][CH:9]=1)[CH3:7])=[O:23]

Participants

5

Reactant 3

HCID 784Hydrogen PeroxideHCID 1140TolueneHCID 53940808HCID 53940808, compound

Product 1

HCID 54303272HCID 54303272, compoundYield 57%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

The difficultly soluble isomer of [1-(2'-fluoro-4-biphenylyl)-ethylsulfinyl]-acetic acid dimethylamide was prepared analogous to Example 51 from [1-(2'-fluoro-4 -biphenylyl)-ethylthio]-acetic acid dimethylamide by oxidation with hydrogen peroxide in glacial acetic acid. Yield: 57% of theory; m.p. 131°-133° C (from toluene)

Sources & evidence

ORD record
ord-a517c60c66094298b34e8c16e74dad63
Source dataset
uspto-grants-1976_11
Patent number
US03993683

Reaction notes

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