Hydrochloric Acid → HCID 131714950, compound

HRID 1731617Notes

Reaction equation

C([N:4]1[C:17]2[CH:16]=[CH:15][C:14]([NH:18][S:19]([CH3:22])(=[O:21])=[O:20])=[CH:13][C:12]=2[O:11][C:10]2[C:5]1=[CH:6][CH:7]=[C:8]([NH:23][S:24]([CH3:27])(=[O:26])=[O:25])[CH:9]=2)(=O)C.[OH-].[Na+].Cl>O>[CH3:22][S:19]([NH:18][C:14]1[CH:15]=[CH:16][C:17]2[NH:4][C:5]3[C:10]([O:11][C:12]=2[CH:13]=1)=[CH:9][C:8]([NH:23][S:24]([CH3:27])(=[O:26])=[O:25])=[CH:7][CH:6]=3)(=[O:20])=[O:21]

Participants

Conditions

Temperature: 60 °C

Procedure

To a suspension of 0.2 g of the product of Example 3 in 17 ml of water was added 0.3 g of sodium hydroxide. The blue solution was heated to 60° C. for 30 minutes. After cooling to room temperature hydrochloric acid was added until the mixture was acidic. The product was extracted into ethyl acetate then chromatographed on silica gel to give 0.05 g of 3,7-di(methysulfonamido)(10H)phenoxazine, which was identified by spectroscopic analysis.

Workup

additionwas added until the mixture
extractionThe product was extracted into ethyl acetate
customthen chromatographed on silica gel

Sources & evidence

ORD record: ord-d892a5e8cdf445ce95cbbcced4c65c7c
Source dataset: uspto-grants-1986_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04622395

Reaction notes

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