Methacrylonitrile → HCID 13050978, compound

HRID 1731654Notes

Reaction equation

HRID 1731654 reaction equation
[Na].[Cl:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([NH:9][NH2:10])[N:4]=1.[C:11](#[N:15])[C:12]([CH3:14])=[CH2:13]>C(O)C>[NH2:15][C:11]1[CH:12]([CH3:14])[CH2:13][N:9]([C:5]2[CH:6]=[CH:7][CH:8]=[C:3]([Cl:2])[N:4]=2)[N:10]=1

Participants

5

Reactant 3

HCID 31368MethacrylonitrileHCID 3200042-Chloro-6-hydrazinopyridineHCID 5360545Sodium

Product 1

HCID 13050978HCID 13050978, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

As for Example 2 a 0.32 g. amount of sodium metal is dissolved in 100 ml. of absolute ethanol, then 10.0 g. of 2-chloro-6-hydrazinopyridine is added, followed by 4.8 g. of methacrylonitrile in place of acrylonitrile. The procedure of Example 2 is followed to give 9.4 g. of crude product. The material is recrystallized from dichloromethane-hexane to give the product of the Example as pale yellow crystals, m.p. 175°-176° C.

Workup

  1. customto give 9.4 g
  2. customThe material is recrystallized from dichloromethane-hexane
  3. customto give the product of the Example as pale yellow crystals, m.p. 175°-176° C.

Sources & evidence

ORD record
ord-b3bc17991c6f4a1e8138691b9d5cdb4f
Source dataset
uspto-grants-1986_11
Patent number
US04622401

Reaction notes

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