Acetate → 7-bromoquinazoline

HRID 173192Notes

Reaction equation

HRID 173192 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[cH:6][n:7][c:8]([I:12])[n:9][c:10]2[cH:11]1.[CH:32]([OH:33])=[O:34].[O-:41][C:42]([CH3:43])=[O:44].[O-:45][C:46]([CH3:47])=[O:48].[O:35]=[CH:36][N:37]([CH3:38])[CH3:39].[Pd+2:40].[c:13]1([P:14]([c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[cH:27][cH:28][cH:29][cH:30][cH:31]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]2[cH:6][n:7][cH:8][n:9][c:10]2[cH:11]1

Participants

7

Reactant 6

HCID 175Acetate2×HCID 284Formic AcidHCID 6228DimethylformamideHCID 11776TriphenylphosphineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 77174867HCID 77174867, compound

Product 1

HCID 111951467-bromoquinazoline

Sources & evidence

ORD record
ord-565f7acab1304903bd51f8c0faddb1ee
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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