反应详情

26.3 g of ethyl 2-methylene-4-phenylbutyrate (1.4) and 4 g of methylamine in 150 ml of ethanol in an autoclave were heated at 80° C. for 10 hours. After cooling down, the ethanol was removed, the residue was taken up in 1N HCl, this was extracted with ether, made alkaline with sodium carbonate and again extracted, dried and evaporated.

1. temperatureAfter cooling down
2. customthe ethanol was removed
3. extractionthis was extracted with ether
4. extractionagain extracted
5. customdried
6. customevaporated