O-Xylene → HCID 178508879, compound

HRID 1732086Notes

Reaction equation

HRID 1732086 reaction equation
[C:1](=[O:4])(O)O.[NH2:5][C:6]([NH2:8])=[NH:7].[C:9]1([CH3:16])[C:10]([CH3:15])=[CH:11][CH:12]=[CH:13][CH:14]=1>>[NH2:7][C:6]1[N:8]=[C:1]([OH:4])[C:9]2[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:15][CH2:13][CH2:14][CH2:9][CH2:10][C:16]=2[N:5]=1

Participants

3

Reactant 2

HCID 7237O-XyleneHCID 286947Carbonic acid-guanidine (1:1)

Product 1

HCID 178508879HCID 178508879, compound

Procedure

A mixture of ethyl-2-cyclododecanone carboxylate (4.0 g) and guanidine carbonate (3.12 g) in xylene (50 ml) was refluxed overnight; after cooling the white solid was collected by filtration, washed with water, and recrystallized from ethanol. 2.15 g of a white powder were recovered.

Workup

  1. temperaturewas refluxed overnight
  2. temperatureafter cooling the white solid
  3. filtrationwas collected by filtration
  4. washwashed with water
  5. customrecrystallized from ethanol
  6. custom2.15 g of a white powder were recovered

Sources & evidence

ORD record
ord-50ffcf5965804de9a5efd745c8a85605
Source dataset
uspto-grants-1986_11
Patent number
US04625026

Reaction notes

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