反应详情

341 mg (1 mmole) of 2-[3-chloro-4-(4-chloropyrazol-1-yl)phenyl]propionic acid tert.-butylester are heated to the boil for 2 hours with 10 mg of p-toluenesulfonic acid in toluene. The reaction solution is washed with water, dried and concentrated to obtain 270 mg (94.7% of theory) of 2-[3-chloro-4-(4-chloropyrazol-1-yl)phenyl]propionic acid (m.p. 102° to 103° C.).

1. washThe reaction solution is washed with water
2. customdried
3. concentrationconcentrated