Dimethyl Sulfate → HCID 178460710, compound

HRID 1733370Notes

Reaction equation

HRID 1733370 reaction equation
[NH:1]=[C:2]1[CH:7]=[CH:6][C:5]([S:8][CH2:9][CH2:10][CH3:11])=[C:4]([CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:3]1[NH:19][C:20]([NH:22][C:23]([O:25][CH3:26])=[O:24])=[S:21].[OH-].[Ca+2].[OH-].[CH3:30]OS(OC)(=O)=O>CN(C)C=O.O>[NH:1]=[C:2]1[CH:7]=[CH:6][C:5]([S:8][CH2:9][CH2:10][CH3:11])=[C:4]([CH2:12][C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH:3]1[NH:19][C:20](=[N:22][C:23]([O:25][CH3:26])=[O:24])[S:21][CH3:30]

Participants

6

Reactant 3

HCID 6497Dimethyl SulfateHCID 6093208Calcium HydroxideHCID 131711976HCID 131711976, compound

Product 1

HCID 178460710HCID 178460710, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 6228DimethylformamideSolvent

Procedure

To a solution of 1-iminophenylmethyl-2-(3-carbomethoxythioureido)-4-propylthiobenzene (3.88 g.; 0.01 mol) in dimethylformamide (40 ml.) and water (10 ml.) there is added calcium hydroxide (0.74 g.; 0.01 mol). The mixture is stirred at room temperature for four hours and to it there is added dimethylsulfate (1.26 g.). The mixture is stirred at room temperature for four hours and the precipitate collected and dried to afford 1-iminophenylmethyl-2-(3-carbomethoxy-S-methylisothioureido)-4-propylthiobenzene.

Workup

  1. stirringThe mixture is stirred at room temperature for four hours
  2. customthe precipitate collected
  3. customdried

Sources & evidence

ORD record
ord-2792c53534d941138fb7c5887846b738
Source dataset
uspto-grants-1980_12
Patent number
US04241079

Reaction notes

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