Water → HCID 178502515, compound

HRID 1733373Notes

Reaction equation

HRID 1733373 reaction equation
[NH:1]=[C:2]1[C:15]([NH:16][C:17]([NH:19][C:20]([O:22][CH3:23])=[O:21])=[S:18])=[CH:14][CH:13]=[C:4]([C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[O:6])[CH:3]1[CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=1[N+:31]([O-:33])=[O:32].[H-].[Na+].S(OC)(O[CH3:39])=O.O>CN(C)C=O>[NH:1]=[C:2]1[C:15]([NH:16][C:17](=[N:19][C:20]([O:22][CH3:23])=[O:21])[S:18][CH3:39])=[CH:14][CH:13]=[C:4]([C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[O:6])[CH:3]1[CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=1[N+:31]([O-:33])=[O:32]

Participants

6

Reactant 4

HCID 962WaterHCID 24758Sodium hydrideHCID 69223Dimethyl sulfiteHCID 131711986HCID 131711986, compound

Product 1

HCID 178502515HCID 178502515, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

To a mixture of 3-imino-(o-nitrophenyl)methyl-4-(3-carbomethoxythioureido)benzophenone (4.62 g.; 0.01 mol) in dimethyl formamide (40 ml.) there is added 57% sodium hydride (0.42 g.; 0.01 mol) (oil dispersion). The mixture is stirred at room temperature for one hour and to it there is added dimethyl sulfite (1.1 g.; 0.01 mol). The mixture is stirred at room temperature for 11/2 hours and is poured into an excess of water. The suspension formed is vacuum filtered and the filter caked dried to afford 3-imino-(o-nitrophenyl)methyl-4-(3-carbomethoxy-S-methylisothioureido)benzophenone.

Workup

  1. stirringThe mixture is stirred at room temperature for 11/2 hours
  2. customThe suspension formed
  3. filtrationfiltered
  4. customthe filter caked dried

Sources & evidence

ORD record
ord-f126d89dd9b54d81b75473a0e71b455c
Source dataset
uspto-grants-1980_12
Patent number
US04241079

Reaction notes

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