Hydrochloric Acid → HCID 20299085, compound

HRID 1733415Notes

Reaction equation

HRID 1733415 reaction equation
C([O:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([CH3:24])(=[N:13][S:14]([C:17]2[CH:23]=[CH:22][C:20]([CH3:21])=[CH:19][CH:18]=2)(=[O:16])=[O:15])=[O:12])=[CH:7][C:6]=1[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])(=O)C.C(=O)([O-])[O-].[Na+].[Na+].C(O)C.Cl>O>[CH2:25]([C:6]1[CH:7]=[C:8]([S:11]([CH3:24])(=[N:13][S:14]([C:17]2[CH:18]=[CH:19][C:20]([CH3:21])=[CH:22][CH:23]=2)(=[O:16])=[O:15])=[O:12])[CH:9]=[CH:10][C:5]=1[OH:4])[CH2:26][CH2:27][CH2:28][CH2:29][CH3:30]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 702EthanolHCID 10340Sodium CarbonateHCID 86737403HCID 86737403, compound

Product 1

HCID 20299085HCID 20299085, compoundYield 89.6%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
50 °C

Procedure

A suspension of 0.8 g of the product of Step C, 30 ml of a saturated sodium carbonate solution and 15 ml of ethanol was stirred at 50° C. for 15 minutes and the solution was cooled in water. The mixture was acidified with concentrated hydrochloric acid and was extracted with ether. The decanted organic phase was evaporated to dryness to obtain 0.65 g of 2-hexyl-4-(S-methyl-N-tosyl-sulfonimidoyl)-phenol which after crystallization from an ether-petroleum ether mixture melted at 107°-109° C.

Workup

  1. extractionwas extracted with ether
  2. customThe decanted organic phase was evaporated to dryness

Sources & evidence

ORD record
ord-fdac9d2f53b042ed964b0e534aea35c9
Source dataset
uspto-grants-1980_12
Patent number
US04242267

Reaction notes

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