反应详情

To a 250 ml round-bottomed flask fitted with a reflux condenser, magnetic stirrer, and argon inlet are added N,N-bis[2-((phenoxycarbonyl)oxy)ethyl]-N-methylamine (25.00 g, 69.6 mmol), acetonitrile (100 ml), and methyl p-toluenesulfonate (12.95 g, 69.6 mmol). After addition is complete, the mixture is heated to reflux for 2 h. The cooled mixture is treated with ether (500 ml). The product precipitates from the mixture and dried to give 5 as a white powder, 31.14 g (81%): mp 117°-118° C.

1. customTo a 250 ml round-bottomed flask fitted with a reflux condenser, magnetic stirrer, and argon inlet
2. additionAfter addition
3. temperaturethe mixture is heated
4. temperatureto reflux for 2 h
5. customThe product precipitates from the mixture
6. customdried