反应详情

0.1 g (0.26 mmol) of 1-benzyl-7-(4-fluorobenzyloxy)-3-hydroxymethyl-2-methylpyrrolo [2,3-d]pyridazine, 0.164 g (0.8 mmol) of dicyclohexylcarbodiimide and 0.046 ml (0.8 mmol) of glacial acetic acid are reacted in 5 ml of anhydrous tetrahydrofuran as described for Example 7a. Yield: 55%, m.p.: 109°-110° C.