Propofol → HCID 19438412, compound

HRID 1734776Notes

Reaction equation

HRID 1734776 reaction equation
Cl[P:2]1[N:5]([C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=2)[P:4](Cl)[N:3]1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[CH:19]([C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([CH:28]([CH3:30])[CH3:29])[C:23]=1[OH:31])([CH3:21])[CH3:20]>C(N(CC)CC)C>[CH:28]([C:24]1[CH:25]=[CH:26][CH:27]=[C:22]([CH:19]([CH3:21])[CH3:20])[C:23]=1[O:31][P:2]1[N:5]([C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=2)[P:4]([O:31][C:23]2[C:24]([CH:28]([CH3:29])[CH3:30])=[CH:25][CH:26]=[CH:27][C:22]=2[CH:19]([CH3:21])[CH3:20])[N:3]1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)([CH3:30])[CH3:29]

Participants

4

Reactant 2

HCID 4943PropofolHCID 15389826HCID 15389826, compound

Product 1

HCID 19438412HCID 19438412, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

The procedure of Example 1 is repeated using 2,4-dichloro-1,3-diphenyl-1,3,2,4-diazadiphosphetidine, 2,6-diisopropylphenol and triethylamine to give the title compound.

Sources & evidence

ORD record
ord-5e49292535b34c14bce7bff4f1731521
Source dataset
uspto-grants-1996_07
Patent number
US05534646

Reaction notes

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