Propofol → HCID 19438415, compound

HRID 1734777Notes

Reaction equation

HRID 1734777 reaction equation
Cl[P:2]1[N:5]([C:6]([CH3:9])([CH3:8])[CH3:7])[P:4](Cl)[N:3]1[C:11]([CH3:14])([CH3:13])[CH3:12].[CH:15]([C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([CH:24]([CH3:26])[CH3:25])[C:19]=1[OH:27])([CH3:17])[CH3:16]>C(N(CC)CC)C>[CH:24]([C:20]1[CH:21]=[CH:22][CH:23]=[C:18]([CH:15]([CH3:17])[CH3:16])[C:19]=1[O:27][P:2]1[N:5]([C:6]([CH3:9])([CH3:8])[CH3:7])[P:4]([O:27][C:19]2[C:20]([CH:24]([CH3:25])[CH3:26])=[CH:21][CH:22]=[CH:23][C:18]=2[CH:15]([CH3:17])[CH3:16])[N:3]1[C:11]([CH3:14])([CH3:13])[CH3:12])([CH3:26])[CH3:25]

Participants

4

Reactant 2

HCID 4943PropofolHCID 125327951,3-Di-tert-butyl-2,4-dichloro-1,3,2,4-diazadiphosphetidine

Product 1

HCID 19438415HCID 19438415, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

The procedure of Example 1 is repeated using 2,4-dichloro-1,3-di-tert-butyl-1,3,2,4-diazadiphosphetidine, 2,6-diisopropylphenol and triethylamine to give the title compound.

Sources & evidence

ORD record
ord-7edb31762f654788abf44e5cb09c244e
Source dataset
uspto-grants-1996_07
Patent number
US05534646

Reaction notes

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