Ethyl Acetate → 5-Chloro-2-(piperidin-4-YL)pyridine

HRID 173486Notes

Reaction equation

HRID 173486 reaction equation
[CH3:19][CH2:20][O:21][C:22](=[O:23])[CH3:24].[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]2=[CH:13][CH2:12][NH:11][CH2:10][CH2:9]2)[n:6][cH:7]1.[H:14][H:15].[Pt:16](=[O:17])=[O:18]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]2)[n:6][cH:7]1

Participants

5

Reactant 4

HCID 8857Ethyl AcetateHCID 345198Adams' catalystHCID 211055245-Chloro-1',2',3',6'-tetrahydro-2,4'-bipyridineHCID 178418361HCID 178418361, compound

Product 1

HCID 231334175-Chloro-2-(piperidin-4-YL)pyridine

Sources & evidence

ORD record
ord-5a9aa398c53b4afdb29ccc0c342d1ee1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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