Hydrochloric Acid → HCID 19966241, compound

HRID 1734914Notes

Reaction equation

HRID 1734914 reaction equation
[ClH:1].[CH:2]([C:5]1[CH:11]=[CH:10][CH:9]=[C:8]([CH2:12]S(C)=O)[C:6]=1[NH2:7])([CH3:4])[CH3:3].CCCCCC>ClCCCl>[ClH:1].[CH:2]([C:5]1[CH:11]=[CH:10][CH:9]=[C:8]([CH2:12][Cl:1])[C:6]=1[NH2:7])([CH3:4])[CH3:3]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 8058HexaneHCID 19966001HCID 19966001, compound

Product 1

HCID 19966241HCID 19966241, compoundYield 96%

Reagents, catalysts & solvents 1

HCID 111,2-DichloroethaneSolvent

Conditions

Temperature
50 °C

Procedure

Hydrogen chloride gas was introduced for 35 minutes into a solution of 7.74 g of 2-isopropyl-6-methylsulfinylmethylaniline [prepared as described in step (ii) above] in 80 ml of 1,2-dichloroethane warmed at 50° C., with the aid of a gas-inlet tube. The reaction mixture was then cooled to room temperature and 50 ml of hexane were added thereto. The crystals which precipitated were collected by filtration and washed with hexane to give 7.78 g (yield 96%) of the title aniline hydrochloride as a powder.

Workup

  1. temperatureThe reaction mixture was then cooled to room temperature
  2. customThe crystals which precipitated
  3. filtrationwere collected by filtration
  4. washwashed with hexane

Sources & evidence

ORD record
ord-cd3bf0428ba24188a3cca98ab81aec6e
Source dataset
uspto-grants-1996_07
Patent number
US05534529

Reaction notes

Loading…