Sulfuric Acid → HCID 178442091, compound

HRID 1735371Notes

Reaction equation

HRID 1735371 reaction equation
CC(C[AlH]CC(C)C)C.[C:10]([C@H:12]1[CH2:17][CH2:16][C@H:15]([C:18]2[CH:23]=[CH:22][C:21]([C:24]3[CH:29]=[CH:28][C:27]([CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])=[CH:26][CH:25]=3)=[CH:20][CH:19]=2)[CH2:14][CH2:13]1)#N.CCCCC.S(=O)(=O)(O)[OH:41]>CCCCCC.O>[CH:10]([C@H:12]1[CH2:17][CH2:16][C@H:15]([C:18]2[CH:23]=[CH:22][C:21]([C:24]3[CH:29]=[CH:28][C:27]([CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])=[CH:26][CH:25]=3)=[CH:20][CH:19]=2)[CH2:14][CH2:13]1)=[O:41]

Participants

7

Reactant 4

HCID 1118Sulfuric AcidHCID 8003PentaneHCID 14487Diisobutylaluminum hydrideHCID 178442090HCID 178442090, compound

Product 1

HCID 178442091HCID 178442091, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 8058HexaneSolvent

Procedure

112 ml of a 20% solution of DIBALH in hexane are added dropwise to a solution of 33.2 g of 4-(trans-4-cyanocyclohexyl)-4'-pentylbiphenyl in 11 of pentane, and the mixture is stirred for 18 hours. Water is then added dropwise until the evolution of gas subsides and then 200 ml of 25% sulfuric acid are added dropwise. The organic phase is separated off, dried over Na2SO4 and evaporated. Colorless deliquescent crystals are obtained.

Workup

  1. customThe organic phase is separated off
  2. dry with materialdried over Na2SO4
  3. customevaporated
  4. customColorless deliquescent crystals are obtained

Sources & evidence

ORD record
ord-15b9e145424c41aca20609b8fec2d3b2
Source dataset
uspto-grants-1996_07
Patent number
US05536442

Reaction notes

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