Hydrochloric Acid → HCID 19432928, compound

HRID 1736405Notes

Reaction equation

HRID 1736405 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[CH:12]=[CH:11][N:10]=[C:9]1[S:13]([CH2:15][CH2:16][CH2:17][O:18][C:19]1[CH:24]=[CH:23][C:22]([N+:25]([O-:27])=[O:26])=[C:21]([CH:28](OC)[O:29]C)[CH:20]=1)=[O:14].Cl>O1CCCC1>[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[CH:12]=[CH:11][N:10]=[C:9]1[S:13]([CH2:15][CH2:16][CH2:17][O:18][C:19]1[CH:24]=[CH:23][C:22]([N+:25]([O-:27])=[O:26])=[C:21]([CH:28]=[O:29])[CH:20]=1)=[O:14]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19432932HCID 19432932, compound

Product 1

HCID 19432928HCID 19432928, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

3.3 Grams of 1-(2-methylphenyl)-2-[3-(3-dimethoxymethyl-4-nitrophenoxy)propylsulfinyl]imidazole was added to 100 ml of tetrahydrofuran and 10 ml of 4 N hydrochloric acid. The mixture was stirred overnight and extracted with ethyl acetate. The extract was washed with water and an aqueous solution saturated with sodium chloride, dried with magnesium sulfate, and concentrated to obtain 2.8 g of 1-(2-methylphenyl)-2-[3-(3-formyl-4-nitrophenoxy)propylsulfinyl]imidazole as a light yellow oil.

Workup

  1. extractionextracted with ethyl acetate
  2. washThe extract was washed with water
  3. dry with materialan aqueous solution saturated with sodium chloride, dried with magnesium sulfate
  4. concentrationconcentrated

Sources & evidence

ORD record
ord-3678e1fb17214609af0d5121cff3ebef
Source dataset
uspto-grants-1996_07
Patent number
US05541198

Reaction notes

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