Ethyl pyruvate → ethyl (2S)-2-((3,5-dichlorophenyl)amino)propanoate

HRID 1739176Notes

Reaction equation

[Cl:1][C:2]1[CH:3]=[C:4]([CH:6]=[C:7]([Cl:9])[CH:8]=1)[NH2:5].[C:10]([O:15][CH2:16][CH3:17])(=[O:14])[C:11]([CH3:13])=O>>[CH2:16]([O:15][C:10](=[O:14])[C@H:11]([CH3:13])[NH:5][C:4]1[CH:3]=[C:2]([Cl:1])[CH:8]=[C:7]([Cl:9])[CH:6]=1)[CH3:17]

Participants

Reactant 2

HCID 12041Ethyl pyruvate

HCID 122813,5-Dichloroaniline

Product 1

HCID 54318970ethyl (2S)-2-((3,5-dichlorophenyl)amino)propanoate

Procedure

Following General Procedure A above and using 3,5-dichloroaniline (Aldrich) and ethyl pyruvate (Aldrich), the title compound was prepared.

Sources & evidence

ORD record: ord-9ca3ac2198bc47298fb4a81d7429f725
Source dataset: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05965614

Reaction notes

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