Hydrochloric Acid → HCID 67571854, compound

HRID 1739414Notes

Reaction equation

HRID 1739414 reaction equation
[C:1]1([S:7]([CH2:10][CH2:11][CH2:12][O:13][C:14]2[CH:25]=[CH:24][C:17]([CH2:18][N:19]3[CH:23]=[CH:22][N:21]=[CH:20]3)=[CH:16][CH:15]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:26]>CCOCC.COCCOC>[ClH:26].[C:1]1([S:7]([CH2:10][CH2:11][CH2:12][O:13][C:14]2[CH:15]=[CH:16][C:17]([CH2:18][N:19]3[CH:23]=[CH:22][N:21]=[CH:20]3)=[CH:24][CH:25]=2)(=[O:9])=[O:8])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 9928639HCID 9928639, compound

Product 1

HCID 67571854HCID 67571854, compound

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 80711,2-DimethoxyethaneSolvent

Procedure

0.55 g of 1-[4-(3-benzenesulfonylpropyloxy)benzyl]imidazole were dissolved in a mixed solvent of ether and DME, and hydrogen chloride gas was blown into the resultant solution for 5 minutes. The crystals precipitated were separated by filtration, thereby affording 0.49 g of 1-[4-(3-benzenesulfonylpropyloxy)benzyl]imidazole hydrochloride with a melting point of 194-196° C.

Workup

  1. customThe crystals precipitated
  2. customwere separated by filtration

Sources & evidence

ORD record
ord-b5d9078fef034f4fa6b6f6ec2e97886a
Source dataset
uspto-grants-1999_10
Patent number
US05965743

Reaction notes

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