反应详情

To isopropyl alcohol (10 ml) was added 2-amino-5-ethyl-1,3,4-thiadiazole (645 mg) and 4-iodobenzyl bromide (1.49 g), followed by heating under reflux for 2 hours. After the reaction mixture was cooled, the crystals so precipitated were collected by filtration and dried, whereby 1.33 g of the title compound was obtained.

1. temperatureby heating
2. temperatureunder reflux for 2 hours
3. temperatureAfter the reaction mixture was cooled
4. customthe crystals so precipitated
5. filtrationwere collected by filtration
6. customdried