反应详情

To an ice-water cooled suspension of 5 mmol of 2-methyl-N-[4-(pyrrolo[1,2-a]quinoxalin-5(4H)ylcarbonyl)-phenyl]benzamide in 5 ml of tetrahydrofuran is added 5.5 mmol of N-chlorosuccinimide followed by continued stirring in the cold for 10 minutes. The bath is removed and stirring continued for 2.25 hours. The reaction mixture is added to ice-water and extracted with ether. The organic layer is dried and concentrated in vacuo to give the desired product as a solid.

1. customThe bath is removed
2. stirringstirring
3. waitcontinued for 2.25 hours
4. additionThe reaction mixture is added to ice-water
5. extractionextracted with ether
6. customThe organic layer is dried
7. concentrationconcentrated in vacuo