Hydrochloric Acid → Tert-butyl 4-(3-chloro-2-fluorobenzoyl)piperazine-1-carboxylate
Reaction equation
[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1.[CH3:15][N:16]([CH3:17])[CH2:18][CH2:19][CH2:20][N:21]=[C:22]=[N:23][CH2:24][CH3:25].[CH:47]([Cl:48])([Cl:49])[Cl:50].[Cl:36][c:37]1[c:38]([F:46])[c:39]([C:40](=[O:41])[OH:42])[cH:43][cH:44][cH:45]1.[ClH:14].[OH:26][n:27]1[c:28]2[cH:29][cH:30][cH:31][cH:32][c:33]2[n:34][n:35]1>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][N:11]([C:40]([c:39]2[c:38]([F:46])[c:37]([Cl:36])[cH:45][cH:44][cH:43]2)=[O:41])[CH2:12][CH2:13]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-c8803adaa7d14f2f9eeef8fc5c5ccff5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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