反应详情

To a mixture of 379 mg of 47% hydrobromic acid aq. and 10 mL of ethanol was added a solution of 352 mg of (R)-1-(4-chlorophenyl)-3-(4-(2-methoxyethyl)piperazin-1-yl)methyl-2-pyrrolidinone in 10 mL of ethanol. The mixture was stirred at room temperature and then cooled. The precipitated solid was filtered and dried to give 488 mg of the title compound.

1. temperaturecooled
2. filtrationThe precipitated solid was filtered
3. customdried