Tert-Butylamine → HCID 54713534, compound

HRID 1740715Notes

Reaction equation

HRID 1740715 reaction equation
[OH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[NH:5][C:4](=[O:12])[C:3]=1[C:13]([O:15]C)=O.[C:17]([NH2:21])([CH3:20])([CH3:19])[CH3:18]>C(O)C>[C:17]([NH:21][C:13]([C:3]1[C:4](=[O:12])[NH:5][C:6]2[C:11]([C:2]=1[OH:1])=[CH:10][CH:9]=[CH:8][CH:7]=2)=[O:15])([CH3:20])([CH3:19])[CH3:18]

Participants

4

Reactant 2

HCID 6385Tert-ButylamineHCID 54676766Methyl 4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylate

Product 1

HCID 54713534HCID 54713534, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

8.76 g (0.04 mol) of methyl 4-hydroxy-2-oxoquinoline-3-carboxylate was stirred with 3.7 g (0.05 mol) of tert-butylamine in 60 ml of ethanol in a miniautoclave for 8 hours at 150° C. under autogenous pressure. After cooling, the crystals were removed by suction filtration, washed with ligroin and dried.

Workup

  1. temperatureAfter cooling
  2. customthe crystals were removed by suction filtration
  3. washwashed with ligroin
  4. customdried

Sources & evidence

ORD record
ord-fd9c455cfe9942979d5f98b368148a6a
Source dataset
uspto-grants-1999_10
Patent number
US05972841

Reaction notes

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