HCID 21834430, compound → HCID 21834422, compound

HRID 1740940Notes

Reaction equation

HRID 1740940 reaction equation
[CH3:1][C:2]1[C:7]([C:8]#[C:9][CH2:10][CH2:11][CH3:12])=[CH:6][N:5]=[C:4]([NH:13][C:14](=[O:19])[C:15]([CH3:18])([CH3:17])[CH3:16])[CH:3]=1>C(OCC)(=O)C.[Pt]=O>[CH3:1][C:2]1[C:7]([CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])=[CH:6][N:5]=[C:4]([NH:13][C:14](=[O:19])[C:15]([CH3:18])([CH3:17])[CH3:16])[CH:3]=1

Participants

4

Reactant 1

HCID 21834430HCID 21834430, compound

Product 1

HCID 21834422HCID 21834422, compound

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 8857Ethyl AcetateSolvent

Procedure

A solution of 4-methyl-2-(trimethylacetyl)amino-5-(1-pentynyl)-pyridine (225 mg, 0.87 mmol) in ethyl acetate (4.5 mL) containing platinum oxide (45 mg) was hydrogenated at atmospheric pressure for 1.5 h. The catalyst was removed by filtration through a Millex-HV 0.45 um Filter Unit. Evaporation of the filtrate gave the title compound.

Workup

  1. customThe catalyst was removed by filtration through a Millex-HV 0.45 um
  2. filtrationFilter Unit
  3. customEvaporation of the filtrate

Sources & evidence

ORD record
ord-fd33297981394917b02fba0ec53daf36
Source dataset
uspto-grants-1999_10
Patent number
US05972975

Reaction notes

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