Hydrochloric Acid → (E)-4-[2-[2-[[(p-Methoxyphenyl)sulfonyl]amino]phenyl]ethenyl]pyridine Hydrochloride

HRID 1741017Notes

Reaction equation

HRID 1741017 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([S:9]([NH:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2/[CH:19]=[CH:20]/[C:21]2[CH:26]=[CH:25][N:24]=[CH:23][CH:22]=2)(=[O:11])=[O:10])=[CH:5][CH:4]=1.[ClH:27]>CO>[ClH:27].[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([S:9]([NH:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2/[CH:19]=[CH:20]/[C:21]2[CH:26]=[CH:25][N:24]=[CH:23][CH:22]=2)(=[O:11])=[O:10])=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 6366736Hmn 154

Product 1

HCID 21834473(E)-4-[2-[2-[[(p-Methoxyphenyl)sulfonyl]amino]phenyl]ethenyl]pyridine Hydrochloride

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

One (1.00) compound obtained in Example 3A was dissolved in 100 ml of methanol followed by addition of hydrogen chloride gas-saturated ethereal solution of 5 times as much by volume under ice-cooling. The solvent was then evaporated off to provide 1.07 g of the title compound as yellow powders. m.p. 258-261° C. (decomp.)

Workup

  1. temperaturecooling
  2. customThe solvent was then evaporated off

Sources & evidence

ORD record
ord-f98c8cbec7424563b3f797c846a5c24e
Source dataset
uspto-grants-1999_10
Patent number
US05972976

Reaction notes

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