反应详情

In the preparation of the creatine acid sulfate salt, the concentration of the sulfuric acid solution is first determined, which is preferably between 31% and 35% sulfuric acid. Then the amount of creatine monohydrate is calculated to provide a molar ratio of creatine to sulfuric acid to be about 2.0:1.0. The amount of creatine monohydrate is then determined from the calculated amount of the anhydrous creatine. Creatine monohydrate is generally preferred since anhydrous creatine can be more easily converted to creatinine than the monohydrate.