Triphenylphosphine → HCID 86751820, compound

HRID 1741324Notes

Reaction equation

HRID 1741324 reaction equation
[C:1]1([C:7]2[CH:8]=[CH:9][C:10]([C:13](=[N:15][O:16][CH:17](O)[CH3:18])[CH3:14])=[N:11][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH:20][C:21]1[CH:53]=[CH:52][C:24]([CH2:25][CH:26]2[S:30][C:29](=[O:31])[N:28]([C:32]([C:45]3[CH:50]=[CH:49][CH:48]=[CH:47][CH:46]=3)([C:39]3[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=3)[C:33]3[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=3)[C:27]2=[O:51])=[CH:23][CH:22]=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.N(C(OCC)=O)=NC(OCC)=O>>[C:1]1([C:7]2[CH:8]=[CH:9][C:10]([C:13](=[N:15][O:16][CH2:17][CH2:18][O:20][C:21]3[CH:22]=[CH:23][C:24]([CH2:25][CH:26]4[S:30][C:29](=[O:31])[N:28]([C:32]([C:45]5[CH:46]=[CH:47][CH:48]=[CH:49][CH:50]=5)([C:33]5[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=5)[C:39]5[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=5)[C:27]4=[O:51])=[CH:52][CH:53]=3)[CH3:14])=[N:11][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 4

HCID 11776TriphenylphosphineHCID 220568ethyl N-ethoxycarbonyliminocarbamateHCID 28181265-(4-Hydroxybenzyl)-3-triphenylmethylthiazolidine-2,4-dioneHCID 86754720HCID 86754720, compound

Product 1

HCID 86751820HCID 86751820, compound

Procedure

Following a procedure similar to that described in Example 1(a), but using 513 mg of 2-[(1-(5-phenyl-2-pyridyl)ethylideneaminooxy]ethanol (prepared as described in Preparation 39), 1.02 g of 5-(4-hydroxybenzyl)-3-tritylthiazolidine-2,4-dione, 577 mg of triphenylphosphine and 383 mg of diethyl azodicarboxylate, 1.40 g of the title compound were obtained as a foam-like solid.

Sources & evidence

ORD record
ord-a65d120925154c318f7a240348ada397
Source dataset
uspto-grants-1999_10
Patent number
US05972959

Reaction notes

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