Hydrochloric Acid → HCID 21834621, compound

HRID 1741476Notes

Reaction equation

HRID 1741476 reaction equation
[C:1]([C:3]1[CH:39]=[CH:38][C:6]([CH2:7][N:8]2[C:12]([CH2:13][C:14]([NH:16][CH:17]([CH2:29][NH:30]C(OC(C)(C)C)=O)[C:18]([N:20]([CH3:28])[CH2:21][C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)=[O:19])=[O:15])=[CH:11][N:10]=[CH:9]2)=[CH:5][CH:4]=1)#[N:2].Cl>CCOC(C)=O>[C:1]([C:3]1[CH:4]=[CH:5][C:6]([CH2:7][N:8]2[C:12]([CH2:13][C:14]([NH:16][CH:17]([CH2:29][NH2:30])[C:18]([N:20]([CH3:28])[CH2:21][C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)=[O:19])=[O:15])=[CH:11][N:10]=[CH:9]2)=[CH:38][CH:39]=1)#[N:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 21834649HCID 21834649, compound

Product 1

HCID 21834621HCID 21834621, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

A solution of the product from Example 27 (86.3 mg, 0.163 mmol) in EtOAc (5 ml) at 0° C. was saturated with gaseous HCl and stirred for 15 min. The solvent was evaporated and the title compound was dried in vacuo.

Workup

  1. customat 0° C.
  2. customThe solvent was evaporated
  3. dry with materialthe title compound was dried in vacuo

Sources & evidence

ORD record
ord-ceea0aeffcfc4e73a6cfa132f038a99e
Source dataset
uspto-grants-1999_10
Patent number
US05972984

Reaction notes

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