Potassium Bromide → HCID 18690859, compound

HRID 1741519Notes

Reaction equation

[CH3:1][O:2][C:3](=[O:19])[CH2:4][N:5]1[C:10]([C:11]2C=C[CH:14]=[CH:13][CH:12]=2)=[CH:9][CH:8]=[C:7]([NH2:17])[C:6]1=[O:18].[K+].[Br-]>>[CH3:1][O:2][C:3](=[O:19])[CH2:4][N:5]1[C:10]([CH2:11][CH2:12][CH2:13][CH3:14])=[CH:9][CH:8]=[C:7]([NH2:17])[C:6]1=[O:18]

Participants

Reactant 2

HCID 253877Potassium Bromide

HCID 18690860HCID 18690860, compound

Product 1

HCID 18690859HCID 18690859, compound

Procedure

Methyl[3-amino-1,2-dihydro-2-oxo-6-phenyl-1-pyridyl]acetate (50f), was isolated (86%) as a grey solid: mp. 207-9° C.; IR (KBr) 3473, 3345, 1750, 1644, 1600, 1536, 1443, 1366, 1309, 1212, 1184, 1156; 1H NMR (d6 -DMSO) δ 7.30 (5H, m), 6.54 (1H, d), 6.03 (1H, d), 5.25 (2H, s), 4.49 (2H, s), 3.61 (3H, s).

Sources & evidence

ORD record: ord-ea93cc61e3bf490ea1239fb1113b645d
Source dataset: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05973111

Reaction notes

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