Sodium hydride → HCID 23719342, compound

HRID 1742034Notes

Reaction equation

HRID 1742034 reaction equation
[CH3:1][CH:2]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH:10]([CH3:12])[CH3:11])[C:5]=1[N:13]([S:17]([N:20]([CH2:25][CH2:26][CH2:27][CH3:28])[CH2:21][CH2:22][CH2:23][CH3:24])(=[O:19])=[O:18])[C:14](=[O:16])[O-:15])[CH3:3].[H-].[Na+:30]>O1CCCC1>[Na+:30].[CH3:1][CH:2]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH:10]([CH3:11])[CH3:12])[C:5]=1[N:13]([S:17]([N:20]([CH2:21][CH2:22][CH2:23][CH3:24])[CH2:25][CH2:26][CH2:27][CH3:28])(=[O:19])=[O:18])[C:14](=[O:15])[O-:16])[CH3:3]

Participants

4

Reactant 2

HCID 24758Sodium hydrideHCID 86747323HCID 86747323, compound

Product 1

HCID 23719342HCID 23719342, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

A solution of the 2,6-bis(1-methylethyl)phenyl[(dibutylamino) sulfonyl]carbamate (5.5 g, 13.3 mmol) in 75 mL tetrahydrofuran was added dropwise to a suspension of sodium hydride (0.4 g, 80% dispersion in mineral oil, 13.3 mmol) in 50 mL tetrahydrofuran at 0° C. under an atmosphere of nitrogen. Stirred for 3 hours, gradually warming to room temperature. Concentrated in vacuo and triturated with hexanes to give the title compound, mp 162°-166° C.

Workup

  1. concentrationConcentrated in vacuo
  2. customtriturated with hexanes

Sources & evidence

ORD record
ord-bd93b88216d94ecc9f7aa62625bf9bf8
Source dataset
uspto-grants-1994_08
Patent number
US05336690

Reaction notes

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