HCID 19006947, compound → HCID 15222896, compound

HRID 1742585Notes

Reaction equation

HRID 1742585 reaction equation
[O:1]=[C:2]1[C:11]2[CH:10]=[CH:9][C:8]([C:12]([O:14]C)=[O:13])=[CH:7][C:6]=2[N:5]=[C:4]2[CH:16]=[CH:17][C:18]([C:20]([O:22]CC)=[O:21])=[N:19][N:3]12>Cl>[O:1]=[C:2]1[C:11]2[CH:10]=[CH:9][C:8]([C:12]([OH:14])=[O:13])=[CH:7][C:6]=2[N:5]=[C:4]2[CH:16]=[CH:17][C:18]([C:20]([OH:22])=[O:21])=[N:19][N:3]12

Participants

3

Reactant 1

HCID 19006947HCID 19006947, compound

Product 1

HCID 15222896HCID 15222896, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

A suspension of 2-ethyl 7-methyl 10-oxo-10H-pyridazino[6,1-b]quinazoline-2,7-dicarboxylate (Example 3, Step A) in 10% hydrochloric acid was refluxed under nitrogen for 12 h. The mixture was cooled and filtered to give the titled compound as a yellow solid, mp>360° C.

Workup

  1. temperaturewas refluxed under nitrogen for 12 h
  2. temperatureThe mixture was cooled
  3. filtrationfiltered

Sources & evidence

ORD record
ord-c9b7400743d14187a671518637859fed
Source dataset
uspto-grants-1994_08
Patent number
US05340808

Reaction notes

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