反应详情

温度

20 °C

The 2-(2-imino-6-trifluoromethoxy-3-benzothiazolinyl)ethanol may be prepared according to the following process: 9.4 g of 2-amino-6-trifluoromethoxybenzothiazole and 10 g of 2-bromoethanol in 30 cm3 of absolute ethanol are heated at boiling temperature for 95 hours. The mixture is then cooled to a temperature in the region of 20° C. The precipitate formed is filtered and washed with 100 cm3 of ethyl ether. 6.4 g of 2-(2-imino-6-trifluoromethoxy-3-benzothiazolinyl)ethanol hydrobromide with a melting point of 219° C. are obtained.

1. customfor 95 hours
2. customThe precipitate formed
3. filtrationis filtered
4. washwashed with 100 cm3 of ethyl ether